(Derogatory) A slut; a tease; a general nuisance; someone who uses sex (or the promise of it) to get what she wants without regard for other people's feelings. Combination of twit and bitch; also referring to someone who walks in a suggestive ("twitchy") manner.
That little twitch stole my best friend's husband.
An annoying species of man, quite unique to this earth. Loud and obnoxious, the Twitch will often present with adult braces. When angry, Twitch's will inherit Don Vito-like tendencies, forming words outside of any formal language.
Look at that Twitch's fuckin' teeth! He's like, 21!