Top Definition
Refers to someone who is extraordinarily dumb, as exhibited by extraordinarily bad choices.

It just refers to someone who is exraordinarily dumb. A derivative of "dumbfucks" from the latin dummass frickinious idiotus.

Dude was a total duffus and used gasoline to start his charcoal for the picnic! Hence the fire department and paramedics
de DustyDude 03 Iunie 2015
Name for the worst people in existence, also name for vagina or something thats broken.
Duff: "My name is @##$ Duffus"
Bystandard: "How do you sleep at night"
de Patrick!@#$%%^^ 13 Aprilie 2006
A long, thick, uncircumcised penis; The best sex any member of the female species could hope for.
That guy had quite the duffus!

I had some duffus last night..... it was phenomenal!
de imsothug 29 Aprilie 2011

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