1. abbreviated from down-syndrome

2. more commonly used to describe someone who appears and acts like a spastic and is either extremely retarded or un-co
bob is a lazy eyed downer who deserves to be shot
de Hugh_11 27 Septembrie 2005

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Someone who suffers from the ever popular "Syndrome of a Down". Usually sports a hideously deformed face and torso, crooked almond eyes and drools constantly. Known for ruining innocent, unsuspecting couples' lives with thier selfishness, they are generally an embarrassment to their families. They generally meander around causing unnecessary noise and offending people with their mere existence in cases where "too-nice-for-their-own-good" families have decided not to abort them or throw them to the wolves shortly after birth.
"That dude's a downer - notice the almond shaped eyes, hunched back and pulsating tongue, complete with an incessant flow of drool. Where's the shotgun?"
de Jes O'Briar 10 Martie 2008

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What extreme System of a Down fans call themselves. Most likely because they are the most kick ass band out there.
Slipknot fans are maggots, System fans are downers.

Tom: Dude I love SOAD.

Jim: You're such a downer.
de beanerwithaweiner 29 Iunie 2006

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drugs that are depressants. Drugs like weed.
druggie:"Do you have any uppers"
dealer:"No man only downers."
druggie:*"well when can I see mary jane? I wanna take her on a cheap date."
Last sentence is code for, do you have any weed for cheap.?
de Insane 07 Februarie 2004

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Often used in central London and suburban areas for describing not only the side effects of certain drugs, but also an emotional state. Downers, a most versatile word, can be used for a multitude of purposes.
That guy is on the downers.
Your so downers.
this is downers, whens the next train?
your mum is so downers.
Your sexual preferences are on the D (shortened illiteration).
de Jambowana 31 Mai 2005

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All the dumb ass holes on here who vote "Thumbs Down" on some of the most awesome and understandable stuff on this site.
Damn!Who could posibly vote "Thumbs Down" on THIS!Damn thoughs Downers!
de Darka 31 Octombrie 2007

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Those annoying shits who put a thumbs down on every definition of a word.
That guy is such a dick. I took my definition out of the dictionary, he still gives it a thumbs down. I'm like WTF! He's one of those downers
de Josh King 03 Noiembrie 2007

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